A review in Molecular Biology Reports argues that managing antifungal resistance in allergic bronchopulmonary aspergillosis (ABPA) requires a One Health approach — one that considers human, animal, and environmental drivers of resistance together rather than in isolation.
ABPA is a hypersensitivity lung condition caused by Aspergillus fumigatus, the same mold genus repeatedly implicated in water-damaged buildings and indoor air contamination. The authors, led by Falcon RMG, point to the growing problem of azole-resistant Aspergillus strains, including resistance that appears to be driven by agricultural use of fungicides in the environment.
The piece reflects a broader shift in fungal disease research: treating mold-related illness in humans cannot be separated from how molds are encountered in homes, agriculture, and the wider environment.